UNITE 2nd Open Call for Interregional Digital Health Innovation Proposals

Are you a digital health innovator in one of the UNITE regions?

The Second UNITE Open Call, offering €6 million in financial support for breakthrough solutions that will transform European healthcare, is now open.

UNITE Framework

UNITE is a major €20 million pan-European programme under the European Commission's Regional Innovation Valleys initiative, which builds a borderless European digital health innovation ecosystem and drives healthcare transformation through digital deep-tech solutions, addressing challenges posed by demographic transitions and ageing populations.

Key Call Details & Timeline

Important Dates:

Call opening: September 10, 2026

Information session: September 30, 2026 (register here)

Submission deadline: December 10, 2026

Project duration: April 1, 2027 – September 30, 2028 (18 months)

Financial Support:

Total budget: €6,000,000

Maximum funding per project: €1,000,000

Maximum funding per organisation: €600,000 (including all UNITE open calls)

Innovation Challenges

The second UNITE Open Call supports innovative digital solutions addressing two key challenges:

1. Deep-tech innovations to secure equal health for the entire population

Solutions that:

- Support greater autonomy for elderly and disadvantaged populations

- Deliver more personalised care tailored to individual health needs

- Integrate fragmented healthcare services

2. Digital solutions to battle the health workforce crisis

Solutions that:

- Alleviate healthcare staff shortages through digital tools and automation

- Streamline clinical workflows and improve operational efficiency

- Address skill gaps through accessible training, education, and upskilling opportunities
 

Eligibility & Regional Requirements

Applicants must be legally established in and comply with the requirements of the following UNITE participating regions:

- Central Macedonia, Greece

- Lombardy Region, Italy

- Extremadura Region, Spain

- Aragón Region, Spain

- Scotland, United Kingdom

- Wales, United Kingdom

- Romania, national scope

Consortium Requirements

Each consortium must include minimum 3 organisations from 3 different UNITE regions:

• At least 1 company or other close-to-market solution provider
• At least 1 research entity supporting the company from any perspective
• At least 1 end-user organization demonstrating the solution in real-life settings

Each consortium must respect the regional balance and include:

• At least 1 organisation from a strong innovation region (Wales, Scotland)
• At least 1 organisation from a moderate or emerging region (Central Macedonia, Romania, Lombardy, Extremadura, Aragón)
  
  

Ecosystem Value and Support

The UNITE’s borderless European digital health innovation ecosystem offers access to:

• Financial support up to €1 million per project
• Tailored matchmaking opportunities with compatible European organisations
• Curated events and networking activities
• Hands-on support to transform ideas into compelling cross-border project proposals
• Over 100 organisations from the private and public sectors, academia, and civil society, spanning all UNITE regions
  
  

Prepare Now

The future of digital health in Europe is taking shape. Be ready to seize this €6 million opportunity and start building your winning partnerships today on the UNITE Matchmaking Platform. 

Please read the UNITE Open Call Documents carefully to ensure compliance with the UNITE framework and regional requirements, and submit your proposal on the UNITE Cloud to receive financial support to advance your digital health solution.